Isolation of Intrinsically Active (MEK-independent) Variants of the ERK Family of Mitogen-activated Protein (MAP) Kinases

MAPKs are key components of cell signaling pathways with a unique activation mechanism: i.e. dual phosphorylation of neighboring threonine and tyrosine residues. The ERK enzymes form a subfamily of MAPKs involved in proliferation, differentiation, development, learning, and memory. The exact role of...

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Bibliografiske detaljer
Main Authors: Levin-Salomon, Vered, Kogan, Konstantin, Ahn, Natalie G., Livnah, Oded, Engelberg, David
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2008
Fag:
Mechanisms of Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259889/
https://ncbi.nlm.nih.gov/pubmed/18829462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806443200
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