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Distinct Roles of TRF1 in the Regulation of Telomere Structure and Lengthening

The telomere is a functional chromatin structure that consists of G-rich repetitive sequences and various associated proteins. Telomeres protect chromosomal ends from degradation, provide escape from the DNA damage response, and regulate telomere lengthening by telomerase. Multiple proteins that loc...

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Hlavní autoři: Okamoto, Keiji, Iwano, Tomohiko, Tachibana, Makoto, Shinkai, Yoichi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259774/
https://ncbi.nlm.nih.gov/pubmed/18587156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802395200
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