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The Structural Basis for Allosteric Inhibition of a Threonine-sensitive Aspartokinase

The commitment step to the aspartate pathway of amino acid biosynthesis is the phosphorylation of aspartic acid catalyzed by aspartokinase (AK). Most microorganisms and plants have multiple forms of this enzyme, and many of these isofunctional enzymes are subject to feedback regulation by the end pr...

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Detalhes bibliográficos
Main Authors: Liu, Xuying, Pavlovsky, Alexander G., Viola, Ronald E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259663/
https://ncbi.nlm.nih.gov/pubmed/18334478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800760200
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