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Structural Characterization of Inhibitors with Selectivity against Members of a Homologous Enzyme Family

The aspartate biosynthetic pathway provides essential metabolites for many important biological functions, including the production of four essential amino acids. Since this critical pathway is only present in plants and microbes any disruptions will be fatal to these organisms. An early pathway enz...

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Detalhes bibliográficos
Main Authors: Pavlovsky, Alexander G., Liu, Xuying, Faehnle, Christopher R., Potente, Nina, Viola, Ronald E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383612/
https://ncbi.nlm.nih.gov/pubmed/22039970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1747-0285.2011.01267.x
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