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Structure-based Functional Study Reveals Multiple Roles of Transmembrane Segment IX and Loop VIII–IX in NhaA Na(+)/H(+) Antiporter of Escherichia coli at Physiological pH
The three-dimensional crystal structure of Escherichia coli NhaA determined at pH 4 provided the first structural insights into the mechanism of antiport and pH regulation of a Na(+)/H(+) antiporter. However, because NhaA is activated at physiological pH (pH 6.5–8.5), many questions pertaining to th...
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| Główni autorzy: | , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Biochemistry and Molecular Biology
2008
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3259659/ https://ncbi.nlm.nih.gov/pubmed/18387952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800482200 |
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