Lifelong CRF overproduction is associated with altered gene expression and sensitivity of discrete GABA(A) and mGlu receptor subtypes

RATIONALE: Repeated activation of corticotropin-releasing factor (CRF) receptors is associated with increased anxiety and enhanced stress responsivity, which may be mediated via limbic GABAergic and glutamatergic transmission. OBJECTIVE: The present study investigated molecular and functional altera...

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Main Authors: Vinkers, Christiaan H., Hendriksen, Hendrikus, van Oorschot, Ruud, Cook, James M., Rallipalli, Sundari, Huang, Shengming, Millan, Mark J., Olivier, Berend, Groenink, Lucianne
Format: Artigo
Jezik:Inglês
Izdano: Springer-Verlag 2011
Teme:
Original Investigation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259347/
https://ncbi.nlm.nih.gov/pubmed/21833506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-011-2423-0
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