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5-HT(1A) receptor blockade reverses GABA(A) receptor α(3) subunit-mediated anxiolytic effects on stress-induced hyperthermia

RATIONALE: Stress-related disorders are associated with dysfunction of both serotonergic and GABAergic pathways, and clinically effective anxiolytics act via both neurotransmitter systems. As there is evidence that the GABA(A) and the serotonin receptor system interact, a serotonergic component in t...

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Bibliografiske detaljer
Main Authors: Vinkers, Christiaan H., van Oorschot, Ruud, Korte, S. Mechiel, Olivier, Berend, Groenink, Lucianne
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892061/
https://ncbi.nlm.nih.gov/pubmed/20535452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-010-1895-7
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