TMPRSS2-ERG -specific transcriptional modulation is associated with prostate cancer biomarkers and TGF-β signaling

BACKGROUND: TMPRSS2-ERG gene fusions occur in about 50% of all prostate cancer cases and represent promising markers for molecular subtyping. Although TMPRSS2-ERG fusion seems to be a critical event in prostate cancer, the precise functional role in cancer development and progression is still unclea...

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Bibliografiske detaljer
Main Authors: Brase, Jan C, Johannes, Marc, Mannsperger, Heiko, Fälth, Maria, Metzger, Jennifer, Kacprzyk, Lukasz A, Andrasiuk, Tatjana, Gade, Stephan, Meister, Michael, Sirma, Hüseyin, Sauter, Guido, Simon, Ronald, Schlomm, Thorsten, Beißbarth, Tim, Korf, Ulrike, Kuner, Ruprecht, Sültmann, Holger
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259213/
https://ncbi.nlm.nih.gov/pubmed/22142399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-507
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