TMPRSS2-ERG -specific transcriptional modulation is associated with prostate cancer biomarkers and TGF-β signaling

BACKGROUND: TMPRSS2-ERG gene fusions occur in about 50% of all prostate cancer cases and represent promising markers for molecular subtyping. Although TMPRSS2-ERG fusion seems to be a critical event in prostate cancer, the precise functional role in cancer development and progression is still unclea...

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Detalhes bibliográficos
Main Authors: Brase, Jan C, Johannes, Marc, Mannsperger, Heiko, Fälth, Maria, Metzger, Jennifer, Kacprzyk, Lukasz A, Andrasiuk, Tatjana, Gade, Stephan, Meister, Michael, Sirma, Hüseyin, Sauter, Guido, Simon, Ronald, Schlomm, Thorsten, Beißbarth, Tim, Korf, Ulrike, Kuner, Ruprecht, Sültmann, Holger
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259213/
https://ncbi.nlm.nih.gov/pubmed/22142399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-507
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