Anti-AIDS agents 85. Design, synthesis, and evaluation of 1R,2R-dicamphanoyl-3,3-dimethyldihydropyrano-[2,3-c]xanthen-7(1H)-one (DCX) derivatives as novel anti-HIV agents

In this study, 1R,2R-dicamphanoyl-3,3-dimethydihydropyrano[2,3-c]xanthen-7(1H)-one (DCX) derivatives were designed and synthesized as novel anti-HIV agents against both wild-type and nonnucleoside reverse transcriptase (RT) inhibitor-resistant HIV-1 (RTMDR-1) strains. Twenty-four DCX analogs (6-29)...

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Main Authors: Zhou, Ting, Shi, Qian, Chen, Chin-Ho, Huang, Li, Ho, Phong, Morris-Natschke, Susan L., Lee, Kuo-Hsiung
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259201/
https://ncbi.nlm.nih.gov/pubmed/22063755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2011.10.025
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