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α-Synuclein levels modulate Huntington's disease in mice

α-Synuclein and mutant huntingtin are the major constituents of the intracellular aggregates that characterize the pathology of Parkinson's disease (PD) and Huntington's disease (HD), respectively. α-Synuclein is likely to be a major contributor to PD, since overexpression of this protein...

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Autors principals: Corrochano, Silvia, Renna, Maurizio, Carter, Sarah, Chrobot, Nichola, Kent, Rose, Stewart, Michelle, Cooper, Jason, Brown, Steve D.M., Rubinsztein, David C., Acevedo-Arozena, Abraham
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259010/
https://ncbi.nlm.nih.gov/pubmed/22010050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr477
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