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Glyceraldehyde-3-Phosphate Dehydrogenase in Retinal Microvasculature: Implications for the Development and Progression of Diabetic Retinopathy

PURPOSE. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) has been hypothesized as a mediator in the activation of multiple pathways implicated in the pathogenesis of diabetic retinopathy. The objective of this study was to understand the mechanism by which high glucose inactivates GAPDH in retinal...

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Detalhes bibliográficos
Main Authors: Madsen-Bouterse, Sally, Mohammad, Ghulam, Kowluru, Renu A.
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258980/
https://ncbi.nlm.nih.gov/pubmed/19875652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-4171
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