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Assembly of Heterohexameric Trypanosome Hexokinases Reveals That Hexokinase 2 Is a Regulable Enzyme

Glycolysis is essential to Trypanosoma brucei, the protozoan parasite that causes African sleeping sickness in humans and nagana in cattle. Hexokinase (HK), the first enzyme in glycolysis, catalyzes the phosphorylation of glucose to form glucose 6-phosphate. T. brucei harbors two HKs that are 98% id...

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Détails bibliographiques
Auteurs principaux: Chambers, Jeremy W., Kearns, Margaret T., Morris, Meredith T., Morris, James C.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258875/
https://ncbi.nlm.nih.gov/pubmed/18387941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802124200
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