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Assembly of Heterohexameric Trypanosome Hexokinases Reveals That Hexokinase 2 Is a Regulable Enzyme

Glycolysis is essential to Trypanosoma brucei, the protozoan parasite that causes African sleeping sickness in humans and nagana in cattle. Hexokinase (HK), the first enzyme in glycolysis, catalyzes the phosphorylation of glucose to form glucose 6-phosphate. T. brucei harbors two HKs that are 98% id...

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書誌詳細
主要な著者: Chambers, Jeremy W., Kearns, Margaret T., Morris, Meredith T., Morris, James C.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258875/
https://ncbi.nlm.nih.gov/pubmed/18387941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802124200
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