Co-blockade of mecR1/blaR1 signal pathway to restore antibiotic susceptibility in clinical isolates of methicillin-resistant Staphylococcus aureus

INTRODUCTION: Methicillin-resistant Staphylococcus aureus (MRSA) is caused by the production of low-affinity penicillin-binding protein 2a and β-lactamases, which are encoded by mecA and blaZ, respectively. Expressions of the two key genes are mutually regulated by MecI and BlaI. The aim of this stu...

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Bibliografske podrobnosti
Main Authors: Hou, Zheng, Zhou, Ying, Wang, Haifang, Bai, Hui, Meng, Jingru, Xue, Xiaoyan, Luo, Xiaoxing
Format: Artigo
Jezik:Inglês
Izdano: Termedia Publishing House 2011
Teme:
Basic Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258742/
https://ncbi.nlm.nih.gov/pubmed/22295022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/aoms.2011.23404
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