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DNA methyltransferase 3a limits the expression of interleukin-13 in T helper 2 cells and allergic airway inflammation

The inverse correlation between DNA methylation and lineage-specific gene expression during T helper cell development is well documented. However, the specific functions of the de novo methyltransferases Dnmt3a and Dnmt3b in cytokine gene regulation have not been defined. We demonstrate that the exp...

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Detaylı Bibliyografya
Asıl Yazarlar: Yu, Qing, Zhou, Baohua, Zhang, Yanlu, Nguyen, Evelyn T., Du, Jianguang, Glosson, Nicole L., Kaplan, Mark H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258606/
https://ncbi.nlm.nih.gov/pubmed/22190484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103803109
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