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DNA methyltransferase 3a limits the expression of interleukin-13 in T helper 2 cells and allergic airway inflammation
The inverse correlation between DNA methylation and lineage-specific gene expression during T helper cell development is well documented. However, the specific functions of the de novo methyltransferases Dnmt3a and Dnmt3b in cytokine gene regulation have not been defined. We demonstrate that the exp...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3258606/ https://ncbi.nlm.nih.gov/pubmed/22190484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103803109 |
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