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A role for neuronal cAMP responsive-element binding (CREB)-1 in brain responses to calorie restriction
Calorie restriction delays brain senescence and prevents neurodegeneration, but critical regulators of these beneficial responses other than the NAD(+)-dependent histone deacetylase Sirtuin-1 (Sirt-1) are unknown. We report that effects of calorie restriction on neuronal plasticity, memory and socia...
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| Главные авторы: | , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3258594/ https://ncbi.nlm.nih.gov/pubmed/22190495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1109237109 |
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