A role for neuronal cAMP responsive-element binding (CREB)-1 in brain responses to calorie restriction

Calorie restriction delays brain senescence and prevents neurodegeneration, but critical regulators of these beneficial responses other than the NAD(+)-dependent histone deacetylase Sirtuin-1 (Sirt-1) are unknown. We report that effects of calorie restriction on neuronal plasticity, memory and socia...

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Main Authors: Fusco, Salvatore, Ripoli, Cristian, Podda, Maria Vittoria, Ranieri, Sofia Chiatamone, Leone, Lucia, Toietta, Gabriele, McBurney, Michael W., Schütz, Günther, Riccio, Antonella, Grassi, Claudio, Galeotti, Tommaso, Pani, Giovambattista
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2012
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258594/
https://ncbi.nlm.nih.gov/pubmed/22190495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1109237109
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