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Loss of immunological tolerance in Gimap5-deficient mice is associated with loss of Foxo in CD4(+) T cells

Previously, we reported the abrogation of quiescence and reduced survival in lymphocytes from Gimap5(sph/sph) mice, an ENU germline mutant with a missense mutation in the GTPase of immunity-associated nucleotide binding protein 5 (Gimap5). These mice showed a progressive loss of peripheral lymphocyt...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Aksoylar, H. Ibrahim, Lampe, Kristin, Barnes, Michael J., Plas, David R., Hoebe, Kasper
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258489/
https://ncbi.nlm.nih.gov/pubmed/22106000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101206
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