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Absence of Runx3 expression in normal gastrointestinal epithelium calls into question its tumour suppressor function

The Runx3 transcription factor regulates cell fate decisions during embryonic development and in adults. It was previously reported that Runx3 is strongly expressed in embryonic and adult gastrointestinal tract (GIT) epithelium (Ep) and that its loss causes gastric cancer. More than 280 publications...

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Détails bibliographiques
Auteurs principaux: Levanon, Ditsa, Bernstein, Yael, Negreanu, Varda, Bone, Karen Rae, Pozner, Amir, Eilam, Raya, Lotem, Joseph, Brenner, Ori, Groner, Yoram
Format: Artigo
Langue:Inglês
Publié: WILEY-VCH Verlag 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258485/
https://ncbi.nlm.nih.gov/pubmed/21786422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201100168
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