Absence of Runx3 expression in normal gastrointestinal epithelium calls into question its tumour suppressor function

The Runx3 transcription factor regulates cell fate decisions during embryonic development and in adults. It was previously reported that Runx3 is strongly expressed in embryonic and adult gastrointestinal tract (GIT) epithelium (Ep) and that its loss causes gastric cancer. More than 280 publications...

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Detalhes bibliográficos
Main Authors: Levanon, Ditsa, Bernstein, Yael, Negreanu, Varda, Bone, Karen Rae, Pozner, Amir, Eilam, Raya, Lotem, Joseph, Brenner, Ori, Groner, Yoram
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258485/
https://ncbi.nlm.nih.gov/pubmed/21786422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201100168
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