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Absence of Runx3 expression in normal gastrointestinal epithelium calls into question its tumour suppressor function

The Runx3 transcription factor regulates cell fate decisions during embryonic development and in adults. It was previously reported that Runx3 is strongly expressed in embryonic and adult gastrointestinal tract (GIT) epithelium (Ep) and that its loss causes gastric cancer. More than 280 publications...

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Autors principals: Levanon, Ditsa, Bernstein, Yael, Negreanu, Varda, Bone, Karen Rae, Pozner, Amir, Eilam, Raya, Lotem, Joseph, Brenner, Ori, Groner, Yoram
Format: Artigo
Idioma:Inglês
Publicat: WILEY-VCH Verlag 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258485/
https://ncbi.nlm.nih.gov/pubmed/21786422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201100168
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