Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies

AIMS: Lipoprotein-associated phospholipase A2 (Lp-PLA2) generates proinflammatory and proatherogenic compounds in the arterial vascular wall and is a potential therapeutic target in coronary heart disease (CHD). We searched for genetic loci related to Lp-PLA2 mass or activity by a genome-wide associ...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Grallert, Harald, Dupuis, Josée, Bis, Joshua C., Dehghan, Abbas, Barbalic, Maja, Baumert, Jens, Lu, Chen, Smith, Nicholas L., Uitterlinden, André G., Roberts, Robert, Khuseyinova, Natalie, Schnabel, Renate B., Rice, Kenneth M., Rivadeneira, Fernando, Hoogeveen, Ron C., Fontes, João Daniel, Meisinger, Christa, Keaney, John F., Lemaitre, Rozenn, Aulchenko, Yurii S., Vasan, Ramachandran S., Ellis, Stephen, Hazen, Stanley L., van Duijn, Cornelia M., Nelson, Jeanenne J., März, Winfried, Schunkert, Heribert, McPherson, Ruth M., Stirnadel-Farrant, Heide A., Psaty, Bruce M., Gieger, Christian, Siscovick, David, Hofman, Albert, Illig, Thomas, Cushman, Mary, Yamamoto, Jennifer F., Rotter, Jerome I., Larson, Martin G., Stewart, Alexandre F.R., Boerwinkle, Eric, Witteman, Jacqueline C.M., Tracy, Russell P., Koenig, Wolfgang, Benjamin, Emelia J., Ballantyne, Christie M.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
Matèries:
Clinical Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258449/
https://ncbi.nlm.nih.gov/pubmed/22003152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehr372
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars