Genome-Wide Association Analysis of Soluble ICAM-1 Concentration Reveals Novel Associations at the NFKBIK, PNPLA3, RELA, and SH2B3 Loci

Soluble ICAM-1 (sICAM-1) is an endothelium-derived inflammatory marker that has been associated with diverse conditions such as myocardial infarction, diabetes, stroke, and malaria. Despite evidence for a heritable component to sICAM-1 levels, few genetic loci have been identified so far. To compreh...

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Autors principals: Paré, Guillaume, Ridker, Paul M., Rose, Lynda, Barbalic, Maja, Dupuis, Josée, Dehghan, Abbas, Bis, Joshua C., Benjamin, Emelia J., Shiffman, Dov, Parker, Alexander N., Chasman, Daniel I.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080865/
https://ncbi.nlm.nih.gov/pubmed/21533024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001374
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