Chromatin Insulator Elements Block Transgene Silencing in Engineered Human Embryonic Stem Cell Lines at a Defined Chromosome 13 Locus

Lineage reporters of human embryonic stem cell (hESC) lines are useful for differentiation studies and drug screening. Previously, we created reporter lines driven by an elongation factor 1 alpha (EF1α) promoter at a chromosome 13q32.3 locus in the hESC line WA09 and an abnormal hESC line BG01V in a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: MacArthur, Chad C., Xue, Haipeng, Van Hoof, Dennis, Lieu, Pauline T., Dudas, Miroslav, Fontes, Andrew, Swistowski, Andrzej, Touboul, Thomas, Seerke, Rina, Laurent, Louise C., Loring, Jeanne F., German, Michael S., Zeng, Xianmin, Rao, Mahendra S., Lakshmipathy, Uma, Chesnut, Jonathan D., Liu, Ying
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Mary Ann Liebert, Inc. 2012
Gaiak:
Original Research Reports
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258440/
https://ncbi.nlm.nih.gov/pubmed/21699412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2011.0163
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