Retrovirus silencer blocking by the cHS4 insulator is CTCF independent

Silencing of retrovirus vectors poses a significant obstacle to genetic manipulation of stem cells and their use in gene therapy. We describe a mammalian silencer blocking assay using insulator elements positioned between retrovirus silencer elements and an LCRβ-globin reporter transgene. In transge...

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Dades bibliogràfiques

Publicat a:	Nucleic Acids Res
Autors principals:	Yao, Shuyuan, Osborne, Cameron S., Bharadwaj, Rikki R., Pasceri, Peter, Sukonnik, Tanya, Pannell, Dylan, Recillas-Targa, Félix, West, Adam G., Ellis, James
Format:	Artigo
Idioma:	Inglês
Publicat:	Oxford University Press 2003
Matèries:	Articles
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC203325/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12954767/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg742
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