Retrovirus silencer blocking by the cHS4 insulator is CTCF independent
Silencing of retrovirus vectors poses a significant obstacle to genetic manipulation of stem cells and their use in gene therapy. We describe a mammalian silencer blocking assay using insulator elements positioned between retrovirus silencer elements and an LCRβ-globin reporter transgene. In transge...
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| Publicado no: | Nucleic Acids Res |
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| Principais autores: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC203325/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12954767/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg742 |
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