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Sequential administration of bovine and human adenovirus vectors to overcome vector immunity in an immunocompetent mouse model of breast cancer

The potential of a bovine adenovirus serotype 3 (BAd3)-based vector to bypass the human adenoviral serotype 5 (HAd5)-specific neutralizing immune response was evaluated in an immunocompetent mouse model of breast cancer. Initially we monitored vector biodistribution, genome persistence, transgene ex...

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Hlavní autoři: Tandon, Manish, Sharma, Anurag, Vemula, Sai V., Bangari, Dinesh S., Mittal, Suresh K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258359/
https://ncbi.nlm.nih.gov/pubmed/21971215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2011.09.031
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