Comparative Analysis of Vector Biodistribution, Persistence and Gene Expression Following Intravenous Delivery of Bovine, Porcine and Human Adenoviral Vectors in a Mouse Model

Nonhuman adenoviruses including bovine adenovirus serotype 3 (BAd3) and porcine adenovirus serotype 3 (PAd3) can circumvent pre-existing immunity against human adenovirus serotype 5 (HAd5) and are being developed as alternative vectors for gene delivery. To assess the usefulness of these vectors for...

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Bibliographic Details
Main Authors: Sharma, Anurag, Bangari, Dinesh S., Tandon, Manish, Pandey, Aseem, HogenEsch, Harm, Mittal, Suresh K.
Format: Artigo
Language:Inglês
Published: 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728445/
https://ncbi.nlm.nih.gov/pubmed/19211122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.01.008
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