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Comparative Analysis of Vector Biodistribution, Persistence and Gene Expression Following Intravenous Delivery of Bovine, Porcine and Human Adenoviral Vectors in a Mouse Model
Nonhuman adenoviruses including bovine adenovirus serotype 3 (BAd3) and porcine adenovirus serotype 3 (PAd3) can circumvent pre-existing immunity against human adenovirus serotype 5 (HAd5) and are being developed as alternative vectors for gene delivery. To assess the usefulness of these vectors for...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2728445/ https://ncbi.nlm.nih.gov/pubmed/19211122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.01.008 |
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