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Persistence and the state of bovine and porcine adenoviral vector genomes in human and nonhuman cell lines
The state of vector genome in transduced cells influences the duration of transgene expression and can be a safety concern if it gets integrated randomly into the host genome. Although human adenovirus (Ad) serotype 5 (HAd5) mainly persists in a linear episomal form, information regarding the state...
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| Huvudupphovsmän: | , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2011
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3197224/ https://ncbi.nlm.nih.gov/pubmed/21864589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2011.08.002 |
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