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Incorporation of albumin fusion proteins into fibrin clots in vitro and in vivo: comparison of different fusion motifs recognized by factor XIIIa

BACKGROUND: The transglutaminase activated factor XIII (FXIIIa) acts to strengthen pathological fibrin clots and to slow their dissolution, in part by crosslinking active α(2)-antiplasmin (α(2)AP) to fibrin. We previously reported that a yeast-derived recombinant fusion protein comprising α(2)AP res...

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Main Authors: Sheffield, William P, Eltringham-Smith, Louise J
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258216/
https://ncbi.nlm.nih.gov/pubmed/22185689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-11-127
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