A factor XIa-activatable hirudin-albumin fusion protein reduces thrombosis in mice without promoting blood loss

Lignende værker

• Fusion to Human Serum Albumin Extends the Circulatory Half-Life and Duration of Antithrombotic Action of the Kunitz Protease Inhibitor Domain of Protease Nexin 2
  af: William P. Sheffield, et al.
  Udgivet: (2018-02-01)
• Addition of a sequence from α(2)-antiplasmin transforms human serum albumin into a blood clot component that speeds clot lysis
  af: Sheffield, William P, et al.
  Udgivet: (2009)
• Selection and characterization of a DNA aptamer inhibiting coagulation factor XIa
  af: Donkor, David A., et al.
  Udgivet: (2017)
• Incorporation of albumin fusion proteins into fibrin clots in vitro and in vivo: comparison of different fusion motifs recognized by factor XIIIa
  af: Sheffield, William P, et al.
  Udgivet: (2011)
• Fusion of the C-terminal triskaidecapeptide of hirudin variant 3 to alpha1-proteinase inhibitor M358R increases the serpin-mediated rate of thrombin inhibition
  af: Roddick, Leigh Ann, et al.
  Udgivet: (2013)