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A mass spectrometry-guided genome mining approach for natural product peptidogenomics

Peptide natural products exhibit broad biological properties and are commonly produced by orthogonal ribosomal and nonribosomal pathways in prokaryotes and eukaryotes. To harvest this large and diverse resource of bioactive molecules, we introduce Natural Product Peptidogenomics (NPP), a new mass sp...

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Détails bibliographiques
Auteurs principaux: Kersten, Roland D., Yang, Yu-Liang, Xu, Yuquan, Cimermancic, Peter, Nam, Sang-Jip, Fenical, William, Fischbach, Michael A., Moore, Bradley S., Dorrestein, Pieter C.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258187/
https://ncbi.nlm.nih.gov/pubmed/21983601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.684
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