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A mass spectrometry-guided genome mining approach for natural product peptidogenomics

Peptide natural products exhibit broad biological properties and are commonly produced by orthogonal ribosomal and nonribosomal pathways in prokaryotes and eukaryotes. To harvest this large and diverse resource of bioactive molecules, we introduce Natural Product Peptidogenomics (NPP), a new mass sp...

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Autors principals: Kersten, Roland D., Yang, Yu-Liang, Xu, Yuquan, Cimermancic, Peter, Nam, Sang-Jip, Fenical, William, Fischbach, Michael A., Moore, Bradley S., Dorrestein, Pieter C.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258187/
https://ncbi.nlm.nih.gov/pubmed/21983601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.684
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