Human telomerase acts as a hTR-independent reverse transcriptase in mitochondria

Human telomerase reverse transcriptase (hTERT) is localized to mitochondria, as well as the nucleus, but details about its biology and function in the organelle remain largely unknown. Here we show, using multiple approaches, that mammalian TERT is mitochondrial, co-purifying with mitochondrial nucl...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Sharma, Nilesh K., Reyes, Aurelio, Green, Paula, Caron, Matthieu J., Bonini, Marcelo G., Gordon, Donna M., Holt, Ian J., Santos, Janine Hertzog
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2012
Teme:
Genome Integrity, Repair and Replication
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258147/
https://ncbi.nlm.nih.gov/pubmed/21937513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr758
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items