Ubiquitin ligase UBR3 regulates cellular levels of the essential DNA repair protein APE1 and is required for genome stability

APE1 (Ref-1) is an essential human protein involved in DNA damage repair and regulation of transcription. Although the cellular functions and biochemical properties of APE1 are well characterized, the mechanism involved in regulation of the cellular levels of this important DNA repair/transcriptiona...

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Autors principals: Meisenberg, Cornelia, Tait, Phillip S., Dianova, Irina I., Wright, Katherine, Edelmann, Mariola J., Ternette, Nicola, Tasaki, Takafumi, Kessler, Benedikt M., Parsons, Jason L., Tae Kwon, Yong, Dianov, Grigory L.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
Matèries:
Genome Integrity, Repair and Replication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258136/
https://ncbi.nlm.nih.gov/pubmed/21933813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr744
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