Ubiquitin ligase UBR3 regulates cellular levels of the essential DNA repair protein APE1 and is required for genome stability

APE1 (Ref-1) is an essential human protein involved in DNA damage repair and regulation of transcription. Although the cellular functions and biochemical properties of APE1 are well characterized, the mechanism involved in regulation of the cellular levels of this important DNA repair/transcriptiona...

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Main Authors: Meisenberg, Cornelia, Tait, Phillip S., Dianova, Irina I., Wright, Katherine, Edelmann, Mariola J., Ternette, Nicola, Tasaki, Takafumi, Kessler, Benedikt M., Parsons, Jason L., Tae Kwon, Yong, Dianov, Grigory L.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2012
主題:
Genome Integrity, Repair and Replication
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258136/
https://ncbi.nlm.nih.gov/pubmed/21933813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr744
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