Role of Interleukin-23 (IL-23) Receptor Signaling for IL-17 Responses in Human Lyme Disease

Interleukin-23 (IL-23) is known to play a crucial role in the development and maintenance of T helper 17 cells. It has been previously demonstrated that IL-17 is involved in experimental Lyme arthritis, caused by Borrelia burgdorferi bacteria. However, the precise role of the IL-23 receptor (IL-23R)...

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Bibliographic Details
Main Authors: Oosting, Marije, ter Hofstede, Hadewych, van de Veerdonk, Frank L., Sturm, Patrick, Kullberg, Bart-Jan, van der Meer, Jos W. M., Netea, Mihai G., Joosten, Leo A. B.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2011
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257938/
https://ncbi.nlm.nih.gov/pubmed/21896776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05242-11
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