Specific inhibitors of eukaryotic DNA synthesis and DNA polymerase alpha, 3-deoxyaphidicolin and aphidicolin-17-monoacetate.

Of several phytotoxins isolated from culture filtrates of Phoma betae Frank PS-13, an incitant of leaf spot disease of sugar beet, three have been identified as aphidicolin, 3-deoxyaphidicolin and aphidicolin-17-monoacetate. Aphidicolin is a selective inhibitor of eukaryotic DNA polymerase alpha (Ik...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Haraguchi, T, Oguro, M, Nagano, H, Ichihara, A, Sakamura, S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1983
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC325786/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6402759/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/11.4.1197
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