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Comparative Effects of R- and S-equol and Implication of Transactivation Functions (AF-1 and AF-2) in Estrogen Receptor-Induced Transcriptional Activity

Equol, one of the main metabolites of daidzein, is a chiral compound with pleiotropic effects on cellular signaling. This property may induce activation/inhibition of the estrogen receptors (ER) a or b, and therefore, explain the beneficial/deleterious effects of equol on estrogen-dependent diseases...

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Bibliografiske detaljer
Main Authors: Shinkaruk, Svitlana, Carreau, Charlotte, Flouriot, Gilles, Bennetau-Pelissero, Catherine, Potier, Mylène
Format: Artigo
Sprog:Inglês
Udgivet: Molecular Diversity Preservation International 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257646/
https://ncbi.nlm.nih.gov/pubmed/22254026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu2030340
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