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Prenylation inhibitors stimulate both estrogen receptor α transcriptional activity through AF-1 and AF-2 and estrogen receptor β transcriptional activity

INTRODUCTION: We showed in a previous study that prenylated proteins play a role in estradiol stimulation of proliferation. However, these proteins antagonize the ability of estrogen receptor (ER) α to stimulate estrogen response element (ERE)-dependent transcriptional activity, potentially through...

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Autors principals: Cestac, Philippe, Sarrabayrouse, Guillaume, Médale-Giamarchi, Claire, Rochaix, Philippe, Balaguer, Patrick, Favre, Gilles, Faye, Jean-Charles, Doisneau-Sixou, Sophie
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064103/
https://ncbi.nlm.nih.gov/pubmed/15642170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr956
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