Astrocyte pVHL and HIF-α isoforms are required for embryonic-to-adult vascular transition in the eye

Successful transition from embryonic to adult circulation is critical for survival of mammalian organisms. This shift occurs in the central cardiovascular circulation and in the eye as oxygen tension increases. However, its regulation is not well understood. We have used combinatorial gene deletion...

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Detalhes bibliográficos
Main Authors: Kurihara, Toshihide, Westenskow, Peter D., Krohne, Tim U., Aguilar, Edith, Johnson, Randall S., Friedlander, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257537/
https://ncbi.nlm.nih.gov/pubmed/22084310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201107029
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