Gating NO Release from Nitric Oxide Synthase

We have investigated the kinetics of NO escape from Geobacillus stearothermophilus nitric oxide synthase (gsNOS). Previous work has indicated that NO release was gated at position 223 in mammalian enzymes; our kinetics experiments include mutants at that position along with measurements on the wild...

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Bibliographic Details
Main Authors: Whited, Charlotte A., Warren, Jeffrey J., Lavoie, Katherine D., Weinert, Emily E., Agapie, Theodor, Winkler, Jay R., Gray, Harry B.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257399/
https://ncbi.nlm.nih.gov/pubmed/22148177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2069533
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