Gating NO Release from Nitric Oxide Synthase

We have investigated the kinetics of NO escape from Geobacillus stearothermophilus nitric oxide synthase (gsNOS). Previous work has indicated that NO release was gated at position 223 in mammalian enzymes; our kinetics experiments include mutants at that position along with measurements on the wild...

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Bibliografiske detaljer
Main Authors: Whited, Charlotte A., Warren, Jeffrey J., Lavoie, Katherine D., Weinert, Emily E., Agapie, Theodor, Winkler, Jay R., Gray, Harry B.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257399/
https://ncbi.nlm.nih.gov/pubmed/22148177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2069533
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