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Probing the heme-thiolate oxygenase domain of inducible nitric oxide synthase with Ru(II) and Re(I) electron tunneling wires

Nitric oxide synthase (NOS) catalyzes the production of nitric oxide from L-arginine and dioxygen at a thiolate-ligated heme active site. Although many of the reaction intermediates are as yet unidentified, it is well established that the catalytic cycle begins with substrate binding and rate-limiti...

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Detalhes bibliográficos
Main Authors: Whited, Charlotte A., Belliston-Bittner, Wendy, Dunn, Alexander R., Winkler, Jay R., Gray, Harry B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744429/
https://ncbi.nlm.nih.gov/pubmed/19759857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1142/S1088424608000352
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