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Alloimmunization to transfused platelets requires priming of CD4(+) T cells in the splenic microenvironment in a murine model
BACKGROUND: Alloantibodies are a clinically significant sequelae of platelet transfusion, potentially rendering patients refractory to ongoing platelet transfusion support. These antibodies are often IgG class switched, suggesting the involvement of CD4(+) T cell help; however, platelet specific CD4...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3257367/ https://ncbi.nlm.nih.gov/pubmed/21981241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1537-2995.2011.03346.x |
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