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Kinetic Rate Constant Prediction Supports the Conformational Selection Mechanism of Protein Binding

The prediction of protein-protein kinetic rate constants provides a fundamental test of our understanding of molecular recognition, and will play an important role in the modeling of complex biological systems. In this paper, a feature selection and regression algorithm is applied to mine a large se...

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Detalhes bibliográficos
Main Authors: Moal, Iain H., Bates, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257286/
https://ncbi.nlm.nih.gov/pubmed/22253587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002351
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