Brain Phenotype of Transgenic Mice Overexpressing Cystathionine β-Synthase

BACKGROUND: The cystathionine β-synthase (CBS) gene, located on human chromosome 21q22.3, is a good candidate for playing a role in the Down Syndrome (DS) cognitive profile: it is overexpressed in the brain of individuals with DS, and it encodes a key enzyme of sulfur-containing amino acid (SAA) met...

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Main Authors: Régnier, Vinciane, Billard, Jean-Marie, Gupta, Sapna, Potier, Brigitte, Woerner, Stéphanie, Paly, Evelyne, Ledru, Aurélie, David, Sabrina, Luilier, Sabrina, Bizot, Jean-Charles, Vacano, Guido, Kraus, Jan P., Patterson, David, Kruger, Warren D., Delabar, Jean M., London, Jaqueline
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257219/
https://ncbi.nlm.nih.gov/pubmed/22253703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029056
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