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Ras-Related Tumorigenesis Is Suppressed by BNIP3-Mediated Autophagy through Inhibition of Cell Proliferation

Autophagy plays diverse roles in Ras-related tumorigenesis. H-ras(val12) induces autophagy through multiple signaling pathways including Raf-1/ERK pathway, and various ERK downstream molecules of autophagy have been reported. In this study, Bcl-2/adenovirus E1B 19-kDa-interacting protein 3 (BNIP3) i...

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Bibliographic Details
Main Authors: Wu, Shan-Ying, Lan, Sheng-Hui, Cheng, Da-En, Chen, Wei-Kai, Shen, Cheng-Huang, Lee, Ying-Ray, Zuchini, Roberto, Liu, Hsiao-Sheng
Format: Artigo
Language:Inglês
Published: Neoplasia Press Inc. 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257192/
https://ncbi.nlm.nih.gov/pubmed/22241963
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