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Degradative autophagy selectively regulates CCND1 (cyclin D1) and MIR224, two oncogenic factors involved in hepatocellular carcinoma tumorigenesis

Overexpressed CCND1 (cyclin D1) is associated with hepatocellular carcinoma (HCC) and we used 147 tumor tissue samples from HCC patients and 3 murine models to reveal an inverse correlation between low autophagic activity and high CCND1 expression. These 2 phenomena in combination correlated with po...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Autophagy
मुख्य लेखकों: Wu, Shan-Ying, Lan, Sheng-Hui, Liu, Hsiao-Sheng
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Taylor & Francis 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6526824/
https://ncbi.nlm.nih.gov/pubmed/30646811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1569918
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