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Anthrax Lethal and Edema Toxins Fail to Directly Impair Human Platelet Function

Hemorrhage is a prominent clinical manifestation of systemic anthrax. Therefore, we have examined the effects of anthrax lethal and edema toxins on human platelets. We find that anthrax lethal toxin fails to cleave its target, mitogen-activated protein kinase 1, and anthrax edema toxin fails to incr...

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Detalhes bibliográficos
Main Authors: Chauncey, Kassidy M., Szarowicz, Sarah E., Sidhu, Gurjit S., During, Russell L., Southwick, Frederick S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256950/
https://ncbi.nlm.nih.gov/pubmed/22158563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir763
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