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Anthrax Lethal and Edema Toxins Fail to Directly Impair Human Platelet Function

Hemorrhage is a prominent clinical manifestation of systemic anthrax. Therefore, we have examined the effects of anthrax lethal and edema toxins on human platelets. We find that anthrax lethal toxin fails to cleave its target, mitogen-activated protein kinase 1, and anthrax edema toxin fails to incr...

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Bibliographic Details
Main Authors: Chauncey, Kassidy M., Szarowicz, Sarah E., Sidhu, Gurjit S., During, Russell L., Southwick, Frederick S.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256950/
https://ncbi.nlm.nih.gov/pubmed/22158563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir763
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