Anthrax lethal toxin paralyzes actin-based motility by blocking Hsp27 phosphorylation

Inhalation of anthrax causes fatal bacteremia, indicating a meager host immune response. We previously showed that anthrax lethal toxin (LT) paralyzes neutrophils, a major component of innate immunity. Here, we have found that LT also inhibits actin-based motility of the intracellular pathogen Liste...

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Main Authors: During, Russell L, Gibson, Bruce G, Li, Wei, Bishai, Ellen A, Sidhu, Gurjit S, Landry, Jacques, Southwick, Frederick S
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2007
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1864983/
https://ncbi.nlm.nih.gov/pubmed/17446863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601687
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